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hardly worth mentioning
Crashes / Fires:
0 / 0
Injuries / Deaths:
0 / 0
Average Mileage:
69,149 miles

About These NHTSA Complaints:

This data is from the NHTSA — the US gov't agency tasked with vehicle safety. Complaints are spread across multiple & redundant categories, & are not organized by problem.

So how do you find out what problems are occurring? For this NHTSA complaint data, the only way is to read through the comments below. Any duplicates or errors? It's not us.

2006 Mercedes-Benz E350 engine problems

engine problem

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2006 Mercedes-Benz E350 Owner Comments

problem #8

Apr 162014


  • miles


After I fill my gas tank there a strong odor of gasoline both inside and outside of the vehicle, particularly after refueling. Possible problem could be the fuel pump and fuel filter along with the gas tank. The odor is so severe we had to park our car outside the garage after filling. The time we didn't it caused severe illness (nausea) to my wife.

- Lenexa , KS, USA

problem #7

Mar 052014


  • 97,000 miles
The contact owns a 2006 Mercedes-Benz E350. The contact stated that while traveling various speeds, the engine seized. The vehicle was taken to the manufacturer where it was found that the engine needed to be replaced. The vehicle was not repaired. The manufacturer was contacted about the failure. The failure mileage was 97,000.

- Redding, MA, USA

problem #6

Jan 122014

E350 6-cyl

  • 110,000 miles
While driving 70 on hwy, check engine light came on, so I immediately stopped and called a tow truck. Mechanic's diagnosis was that the tumble flap was broken in the air intake manifold. The only fix is replacing the entire manifold for $2000 plus labor, tax and gaskets. The flaps are small and could be an inexpensive fix but all dealerships that I called confirmed that the only fix available is to replace the entire air intake manifold. Research tells me that this is a very common problem on this and many other models within the same years.

- Southlake , TX, USA

problem #5

May 282013

E350 6-cyl

  • 47,951 miles


Purchased 2006 Mercedes-Benz E350 4matic with 47,851 miles on odometer from mattie imports, Inc., fall river, MA on May 27, 2013. Automobile had approximately one-quarter of a tank of gasoline at purchase. Salesperson declined purchaser's request to "top-off" the gas tank prior to buyer leaving sellers lot. On May 28, 2013 buyer filled gas tank with fuel. Buyer immediately noticed a strong gasoline odor which continued after exiting fueling station. Odor progressed from exterior of automobile into automobile cabin. Buyer checked fuel tank filler cap and confirmed it was properly engaged. Buyer inspected the entire automobile for any leaking fluids and found none. The strong odor of gasoline persisted throughout the night while the automobile was parked in buyer's garage. Buyer left the garage door partially open and placed a fan in the opening and set the fan to exhaust in an effort to remove the strong fuel odor. The following morning the strong gasoline odor was still present. Buyer's 13 year old son was unable to withstand the odor and had to cover his nose and mouth while passing through buyer's garage. Buyer has experienced nausea and lightheadedness since being exposed to the odor. Upon research buyer learned that there exists and ongoing NHTSA investigation into this issue and a class-action lawsuit as well.

- Fairhaven, MA, USA

problem #4

Nov 192011


  • 158,510 miles
The contact owns a 2006 Mercedes-Benz E350. The contact stated the check engine light illuminated. The contact took the vehicle to the dealer who stated that the cam shaft was unbalanced and needed to be replaced. The vehicle was not repaired. The failure mileage was 158,510.

- Norwalk, CT, USA

problem #3

Mar 102013

E350 6-cyl

  • 64,000 miles
The contact owns a 2006 Mercedes Benz E-350. The contact stated that while driving approximately 20 mph, the vehicle jerked and the check engine warning light illuminated. The vehicle was taken to a private mechanic where it was diagnosed that the cam shaft needed to be rebuilt. The manufactured was not made aware of the failure. The vehicle was not repaired. The approximate failure mileage and current mileage was 64,000.

- Baltimore, MD, USA

problem #2

Oct 312012


  • miles
I have appr. 64,0000 miles on my Mercedes E350 and the check engine light came on. Sent it to the Mercedes dealership and said that the car had a balance shaft problem. Sold me the car in 2008. Service bulletins were out since 2007. Mercedes will only help minimally with the cost. Total cost so far is $3750. To much for me. Told Mercedes that I would have to drive around in a defective vehicle with my family and asked the rep. If that was safe, he replied "no". rep. Said that there was no campaign out on this problem. Something needs to get done before casualties occur.

- Mooresville, NC, USA

problem #1

Feb 012012

E350 6-cyl

  • 75,729 miles
I had so many problem with my Mercedes E350, but when the engine light was on I couldn't believe was the balance shaft. It was in warranty so I didn't pay a cent but when they returned the car back was not the same any more, the tail light was cracked and the A/C opening are inside. The car is not any more the same, sometimes is shaking, and has so many other problems. I saw online that Mercedes has to many cars with this defects that brings more problems, so I'm asking what are you waiting for a recall"????"

- Boca Raton, FL, USA

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